Primary Identifier | MGI:2676812 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 387146 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; labyrinthine layer development; and long-term synaptic potentiation. Is expressed in several structures, including brain; liver; lung; reproductive system; and tongue. Human ortholog(s) of this gene implicated in lung adenocarcinoma. Orthologous to human MIR127 (microRNA 127). PHENOTYPE: Mice heterozygous for a knock-out allele exhibit increased placenta weight and placental transport when the allele is inherited maternally and reduced placenta weight, decreased placental transport and some neonatal lethality when this allele is inherited paternally. [provided by MGI curators] |