| Primary Identifier | MGI:1924399 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 217893 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transmembrane transporter binding activity. Predicted to be involved in endoplasmic reticulum calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and protein localization to plasma membrane. Predicted to act upstream of or within protein localization to phagophore assembly site. Predicted to be located in endoplasmic reticulum and mitochondrion. Is expressed in several structures, including diaphragm; limb segment; nervous system; sensory organ; and skeletal musculature. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 66. Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2). PHENOTYPE: Mice homozygous for a gene trap allele exhibit decreased sensitivity to TRAIL-induced spleen apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
