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Protein Coding Gene : Dync2i1 dynein 2 intermediate chain 1
Primary Identifier  MGI:2445085 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  217935
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in intraciliary retrograde transport. Located in cilium. Is expressed in mandible; maxilla; olfactory epithelium; and orbito-sphenoid. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 8 with or without polydactyly. Orthologous to human DYNC2I1 (dynein 2 intermediate chain 1).
PHENOTYPE: Mice homozygous for a null allele display embryonic lethality during organogenesis with abnormal head development. [provided by MGI curators]
  • synonyms:
  • dynein 2 intermediate chain 1,
  • WD repeat domain 60,
  • Dync2i1,
  • MGI:6456881,
  • RIKEN cDNA D430033N04 gene,
  • MGI:6458536,
  • Wdr60,
  • Dync2l1,
  • D430033N04Rik
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Trail: ProteinCodingGene

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