| Primary Identifier | MGI:1931527 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 50709 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. A structural constituent of chromatin. Acts upstream of or within chromatin organization and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in early conceptus; oocyte; and secondary oocyte. Orthologous to human H1-4 (H1.4 linker histone, cluster member). PHENOTYPE: Homozygotes for targeted null mutations are normal, but Hist1h1e/Hist1h1c double knockout males are significantly smaller than normal. The Hist1h1e/Hist1h1d/Hist1h1e triple knockout is lethal by embryonic day 12.5, and heterozygotes are underrepresented. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
