| Primary Identifier | MGI:2389216 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 105355 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including toxin transmembrane transporter activity; urate transmembrane transporter activity; and voltage-gated monoatomic anion channel activity. Predicted to be involved in urate metabolic process; urate transport; and xenobiotic detoxification by transmembrane export across the plasma membrane. Predicted to be located in endoplasmic reticulum membrane; perinuclear region of cytoplasm; and plasma membrane. Predicted to be active in apical plasma membrane. Is expressed in several structures, including liver and urinary system. Human ortholog(s) of this gene implicated in gout. Orthologous to human SLC17A3 (solute carrier family 17 member 3). PHENOTYPE: Homozygous null mice show abnormal urinary excretion of endogenous metabolites and abnormal plasma levels of various endogenous metabolites. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
