Primary Identifier | MGI:2685748 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 380836 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in lactate metabolic process and mitochondrial magnesium ion transmembrane transport. Located in mitochondrion. Orthologous to human MRS2 (magnesium transporter MRS2). PHENOTYPE: Homozygous knockout affects mitochondrial Mg2+ uptake and leads to protection against LPS-induced septic shock. [provided by MGI curators] |