| Primary Identifier | MGI:97762 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 19109 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable hormone activity and prolactin receptor binding activity. Acts upstream of or within several processes, including maternal behavior; positive regulation of epithelial cell proliferation; and positive regulation of receptor signaling pathway via JAK-STAT. Located in secretory granule. Is expressed in hippocampus; pituitary gland; placenta; and trophoblast giant cell. Human ortholog(s) of this gene implicated in carotid artery disease; impulse control disorder; and prolactinoma. Orthologous to human PRL (prolactin). PHENOTYPE: Homozygous null female mice have irregular oestrus cycles and are infertile. Defects of the pituitary gland include hyperplasia, which progresses to adenoma, and impaired secretion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
