| Primary Identifier | MGI:1351649 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 27372 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable hormone activity and prolactin receptor binding activity. Predicted to be involved in several processes, including female pregnancy; positive regulation of lactation; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in decidua; extraembryonic component; placenta; and uterus stroma. Used to study hyperandrogenism. PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced female fertility and a male reproductive tract phenotype that includes enlarged testes and seminal vesicles, increased sperm count, increased serum testosterone and luteinizing hormone levels, and abnormal adult Leydig cell differentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
