Primary Identifier | MGI:97619 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 18814 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytokine activity and hormone activity. Acts upstream of or within negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; and placenta blood vessel development. Located in extracellular space. Is expressed in ectoplacental cone; extraembryonic component; placenta; and trophoblast giant cell. PHENOTYPE: Female mice homozygous for a null allele display reduced litter sizes and placental abnormalities that vary with the sex of the fetus. [provided by MGI curators] |