Primary Identifier | MGI:1923737 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 76487 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycogen binding activity and protein phosphatase binding activity. Acts upstream of or within glucose homeostasis; positive regulation of glycogen (starch) synthase activity; and positive regulation of glycogen biosynthetic process. Located in cytoplasm. Part of protein phosphatase type 1 complex. Is expressed in several structures, including adipose tissue; femur; heart; lung; and spleen. Orthologous to human PPP1R3G (protein phosphatase 1 regulatory subunit 3G). PHENOTYPE: Under a high-fat diet, mice homozygous for a knock-out allele show decreased susceptibility to diet-induced obesity and hepatic steatosis along with a higher metabolic rate, increased food intake, and decreased glycogen levels in liver and adipose tissue. [provided by MGI curators] |