| Primary Identifier | MGI:1915654 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 68404 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in presynaptic modulation of chemical synaptic transmission and regulation of synapse maturation. Acts upstream of or within neuron projection extension. Located in extracellular space and plasma membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and liver. Orthologous to human NRN1 (neuritin 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a reduction in body length and body weight, delayed axonal, dendritic, and synaptic development, reduced dendritic spine maintenance leading to gradual spine loss, and impaired associative and spatial learning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
