Primary Identifier | MGI:1924596 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 109254 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable hydrolase activity. Predicted to be involved in several processes, including cell migration involved in sprouting angiogenesis; negative regulation of secretion by cell; and positive regulation of macromolecule metabolic process. Predicted to be located in caveola and cell surface. Predicted to be active in endomembrane system. Orthologous to human ADTRP (androgen dependent TFPI regulating protein). PHENOTYPE: Mice homozygous for one null allele display increased pre-/peri-/neonatal death and vascular abnormalities. Mice homozygous for a second null allele are viable with abnormal hydrolysis of fatty acid esters of hydroxy fatty acids. [provided by MGI curators] |