Primary Identifier | MGI:1338034 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 18676 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone H4K20 demethylase activity. Involved in transcription initiation-coupled chromatin remodeling. Predicted to be located in kinetochore; nucleolus; and nucleoplasm. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Orthologous to human PHF2 (PHD finger protein 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit partial postnatal lethality, decreased body weight, decreased adipocity and impaired adipogenesis. [provided by MGI curators] |