| Primary Identifier | MGI:109278 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 18295 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable growth factor activity. Predicted to be an extracellular matrix structural constituent conferring compression resistance. Predicted to be involved in articular cartilage development; bone development; and negative regulation of smooth muscle cell proliferation. Located in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and skeleton. Orthologous to human OGN (osteoglycin). PHENOTYPE: Mice homozygous for a disruption in this gene display reduced collagen fiber density and organization, as well as more variability in fibrilar diameter in both the skin and the cornea. Corneal clarity was unaffected whereas skin tensile strength was reduced. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
