| Primary Identifier | MGI:1339365 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 13610 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity and integrin binding activity. Acts upstream of or within several processes, including Notch signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and regulation of interleukin-1 beta production. Is active in presynapse. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and retina. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3). PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype although litter sizes are reduced. Susceptibility to pulmonary edema is also reduced. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
