| Primary Identifier | MGI:109244 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 20354 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables receptor ligand activity and semaphorin receptor binding activity. Involved in several processes, including negative regulation of osteoblast differentiation; positive regulation of Rho protein signal transduction; and regulation of peptidyl-tyrosine phosphorylation. Acts upstream of or within positive regulation of axonogenesis. Located in extracellular space. Part of semaphorin receptor complex. Is active in GABA-ergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human SEMA4D (semaphorin 4D). PHENOTYPE: Mice homozygous for disruptions in this gene display functional defects in their immune system but are normal in other systems of the body. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
