| Primary Identifier | MGI:1346325 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 23882 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within negative regulation of protein kinase activity; positive regulation of MAPK cascade; and regulation of cell cycle. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human GADD45G (growth arrest and DNA damage inducible gamma). PHENOTYPE: Mice homozygous for some null alleles exhibit male to female sex reversal, abnormal T-helper 1 and NK physiology, decreased type IV hypersensitivity, altered cellular survival to osmotic stress and impaired adaptive thermogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
