| Primary Identifier | MGI:2685119 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 218268 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in early conceptus and reproductive system. Orthologous to human EIF4E1B (eukaryotic translation initiation factor 4E family member 1B). PHENOTYPE: Homozygous null females are infertile and produce embryos that do not progress beyond the two-cell stage. Mice homozygous for a conditional allele activated in oocytes exhibit female infertility with produced embryos arresting at the two-cell stage during oocyte-to-embryo transition. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
