Primary Identifier | MGI:894682 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 107448 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable netrin receptor activity. Acts upstream of or within anterior/posterior axon guidance. Predicted to be located in neuron projection membrane and neuronal cell body membrane. Is expressed in several structures, including brain; sensory organ; skeleton; ventral grey horn; and vibrissa follicle. Orthologous to human UNC5A (unc-5 netrin receptor A). PHENOTYPE: Homozygous null mice are viable through adulthood but display decreased apoptotic cell death, supernumerary neurons and morphological alterations in the embryonic cervical spinal cord. [provided by MGI curators] |