Primary Identifier | MGI:3487246 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 432763 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable long-chain fatty acid binding activity; protein tyrosine kinase binding activity; and ubiquitin-like protein ligase binding activity. Involved in T cell differentiation in thymus and alpha-beta T cell differentiation. Predicted to be located in several cellular components, including nucleoplasm; perinuclear region of cytoplasm; and postsynaptic density. Predicted to be active in glutamatergic synapse; nucleus; and postsynaptic density, intracellular component. Orthologous to human PRR7 (proline rich 7, synaptic). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and exhibit no major defects in the immune system except for a slight decrease in the number of single positive CD4+ T cells in the thymus. [provided by MGI curators] |