Primary Identifier | MGI:1921636 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 74386 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable nucleotide binding activity. Acts upstream of or within glucose homeostasis; reduction of food intake in response to dietary excess; and response to glucose. Predicted to be located in nucleoplasm. Predicted to be part of RecQ family helicase-topoisomerase III complex. Predicted to be active in nuclear body. Is expressed in embryo. Orthologous to human RMI1 (RecQ mediated genome instability 1). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit decreased weight and increased resistance to diet-induced obesity. [provided by MGI curators] |