| Primary Identifier | MGI:1355275 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 50916 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within heart development. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including autopod; central nervous system; heart; sensory organ; and skin. Orthologous to human IRX4 (iroquois homeobox 4). PHENOTYPE: Homozygotes for a targeted null mutation exhibit abnormal ventricular gene expression followed by cardiomyopathy with hypertrophy and impaired contractile function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
