| Primary Identifier | MGI:105064 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 105243 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables PDZ domain binding activity and sodium:proton antiporter activity. Acts upstream of or within regulation of pH and sodium ion transport. Located in brush border membrane and vesicle. Is expressed in several structures, including 1-cell stage conceptus; 2-cell stage conceptus; 4-8 cell stage conceptus; metanephros; and oocyte. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8; cystic fibrosis; exocrine pancreatic insufficiency; and gastrointestinal system disease. Orthologous to human SLC9A3 (solute carrier family 9 member A3). PHENOTYPE: Homozygous mutant mice have diarrhea associated with defects of renal and intestinal absorption. Males are infertile. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
