Primary Identifier | MGI:1920958 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 73708 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables methylated histone binding activity. Involved in epigenetic programing of female pronucleus. Acts upstream of or within embryonic cleavage. Located in chromatin; cytoplasm; and pronucleus. Is expressed in several structures, including central nervous system; early conceptus; gonad; hindgut diverticulum; and primordial germ cell. Orthologous to human DPPA3 (developmental pluripotency associated 3). PHENOTYPE: Female mice homozygous for a disruption in this gene are infertile or have reduced fertility due to a failure in embryonic development at or before implantation. [provided by MGI curators] |