| Primary Identifier | MGI:1306778 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 17755 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin binding activity; microtubule binding activity; and phospholipid binding activity. Involved in regulation of postsynapse assembly. Acts upstream of or within several processes, including establishment of monopolar cell polarity; mitochondrion transport along microtubule; and neuron projection development. Located in several cellular components, including neuronal cell body; photoreceptor outer segment; and postsynaptic density. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including central nervous system; genitourinary system; intestine smooth muscle circular layer; nose; and trigeminal nerve. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 83 and periventricular nodular heterotopia. Orthologous to human MAP1B (microtubule associated protein 1B). PHENOTYPE: Mice homozygous for one knock-out allele die prior to E8.5. While mice homozygous for other knock-out alleles exhibit behavioral, visual system, and nervous system defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
