Primary Identifier | MGI:5510732 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 102216272 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP binding activity and adenylate kinase activity. Predicted to be involved in several processes, including chromatin looping; nucleoside monophosphate phosphorylation; and ribosome biogenesis. Predicted to be located in Cajal body; centrosome; and nuclear speck. Predicted to be active in cytoplasm and nucleus. Orthologous to human AK6 (adenylate kinase 6). PHENOTYPE: Mice homozygous for a null mutation display prenatal lethality. Mice heterozygous for a null mutation display impaired rRNA processing and reduced protein production during rapid cell growth. [provided by MGI curators] |