| Primary Identifier | MGI:1916298 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 69048 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable zinc efflux transmembrane transporter activity and zinc:proton antiporter activity. Predicted to be involved in several processes, including insulin processing; intracellular zinc ion homeostasis; and zinc ion transmembrane transport. Predicted to act upstream of with a positive effect on GPI anchor biosynthetic process. Predicted to be located in several cellular components, including Golgi apparatus; cytoplasmic vesicle membrane; and nuclear lumen. Predicted to be active in Golgi apparatus and cytoplasmic vesicle. Is expressed in craniocervical region bone; submandibular gland primordium; and thoracic segment skeleton. Orthologous to human SLC30A5 (solute carrier family 30 member 5). PHENOTYPE: Homozygous null mice are growth retarded and exhibit skeletal defects including reduced bone density. The majority of mutant male mice die suddenly when they reach reproductive age due to bradyarrhythmia, whereas female mice live a normal term. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
