| Primary Identifier | MGI:99555 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 238871 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including ATPase binding activity; calcium channel regulator activity; and transmembrane transporter binding activity. Involved in several processes, including cAMP/PKA signal transduction; regulation of calcium ion transmembrane transport; and regulation of heart contraction. Acts upstream of or within several processes, including cellular response to follicle-stimulating hormone stimulus; neutrophil chemotaxis; and ovulation from ovarian follicle. Located in centrosome. Part of potassium channel complex and voltage-gated calcium channel complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in acrodysostosis. Orthologous to human PDE4D (phosphodiesterase 4D). PHENOTYPE: Homozygotes for targeted null mutations exhibit delayed growth, female infertility associated with impaired ovulation, and reduced postnatal viability. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
