| Primary Identifier | MGI:102670 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 13206 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP hydrolysis activity. Involved in male meiosis I; regulatory ncRNA-mediated gene silencing; and spermatogenesis. Acts upstream of with a positive effect on transposable element silencing by piRNA-mediated heterochromatin formation. Acts upstream of or within regulation of protein localization. Located in cytoplasmic ribonucleoprotein granule; nucleus; and perinuclear region of cytoplasm. Part of ribonucleoprotein complex. Is expressed in several structures, including alimentary system mesentery; aorta-gonad-mesonephros; embryo ectoderm; gonad; and gonad primordium. Orthologous to human DDX4 (DEAD-box helicase 4). PHENOTYPE: Spermatogenesis is blocked in homozygous mutant mice, resulting in male infertility. Female mutant mice are fertile and do not exhibit any obvious reproductive defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
