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Protein Coding Gene : Plpp1 phospholipid phosphatase 1
Primary Identifier  MGI:108412 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  19012
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables diacylglycerol diphosphate phosphatase activity and lipid phosphatase activity. Involved in several processes, including phospholipid dephosphorylation; phospholipid metabolic process; and sphingolipid metabolic process. Located in caveola. Is expressed in several structures, including alimentary system; heart; nervous system; respiratory system; and sensory organ. Orthologous to human PLPP1 (phospholipid phosphatase 1).
PHENOTYPE: Mice homozygous for a hypomorphic allele are viable and fertile with elevated plasma levels of lysophosphatidic acid. [provided by MGI curators]
  • synonyms:
  • mPAP,
  • MGD-MRK-37455,
  • hydrogen peroxide inducible protein 53,
  • Plpp1,
  • LPP1,
  • Ppap2a,
  • Lipid phosphate phosphatase 1,
  • MGD-MRK-26084,
  • LPP-1,
  • phospholipid phosphatase 1,
  • phosphatidic acid phosphatase type 2A,
  • Hpic53,
  • MGI:104646
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