| Primary Identifier | MGI:1201784 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 18300 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable carbohydrate binding activity. Acts upstream of or within several processes, including neutrophil homeostasis; neutrophil migration; and positive regulation of macrophage antigen processing and presentation. Located in extracellular space. Is expressed in embryo; esophagus; olfactory epithelium; rectum; and testis. Orthologous to human FAM3D (FAM3 metabolism regulating signaling molecule D). PHENOTYPE: Male mice homozygous for a targeted mutation exhibit emotion/affect abnormalities including decreased anxiety and depression responses. Mice homozygous for a null allele exhibit colitis by 1 year of age, increased sensitivity to chemically-induced colitis associated with high incidence of cancer, abnormal gut flora balance and males show decreased development of induced abdominal aortic aneurysm. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
