Primary Identifier | MGI:1919088 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 71838 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and nuclear speck. Predicted to be active in nucleus. Orthologous to human PHF7 (PHD finger protein 7). PHENOTYPE: Mice homozygous for a conditionally allele activated in sperm or a enzymatic dead allele exhibit male infertility associated with oligozoospermia, asthenozoospermia, teratozoospermia, and defective histone to protamine exchange during spermiogenesis. [provided by MGI curators] |