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Protein Coding Gene : Msmb beta-microseminoprotein
Primary Identifier  MGI:97166 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  17695
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be located in extracellular region. Is expressed in male reproductive gland or organ. Used to study prostate cancer. Orthologous to human MSMB (microseminoprotein beta).
PHENOTYPE: Mice homozygous for a knock-in allele exhibit early prostate cancer development progressing from intraepithelial neoplasia with microinvasion to well-differentiated prostate gland adenocarcinoma, and show enlargement of the prostate gland and the lymph nodes, and increased metastatic potential. [provided by MGI curators]
  • synonyms:
  • beta-inhibin,
  • beta-microseminoprotein,
  • Msmb,
  • beta-MSP,
  • PIP,
  • MGD-MRK-12565,
  • PSP94,
  • prostatic inhibin protein
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