Primary Identifier | MGI:2148204 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 107751 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Acts upstream of or within several processes, including detection of temperature stimulus; nervous system development; and sensory perception of mechanical stimulus. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; and trunk somite. Orthologous to human DRGX (dorsal root ganglia homeobox). PHENOTYPE: Homozygous null mice had delayed projection of sensory afferent neurons in the dorsal, but not the ventral, spinal cord during embryonic development. This delayed development resulted in abnormal responses to noxious stimuli in adults, but normal locomotion and sensory motor function. [provided by MGI curators] |