| Primary Identifier | MGI:2443514 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 218973 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity; RNA polymerase binding activity; and chromatin binding activity. Acts upstream of or within RNA processing; pericentric heterochromatin organization; and regulation of chromosome organization. Located in chromosome, centromeric region. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system; liver; and submandibular gland primordium. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Orthologous to human WDHD1 (WD repeat and HMG-box DNA binding protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality between E7.5 and E8.5, reduced body size, decreased cell proliferation, and increased cell apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
