| Primary Identifier | MGI:1914332 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 67082 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in energy homeostasis. Located in cytoplasmic vesicle and plasma membrane. Is expressed in several structures, including gut; metanephros; neural tube; testis; and yolk sac. Orthologous to human CCDC198 (coiled-coil domain containing 198). PHENOTYPE: On the FVB/Ant background knockout mice show increased body weight, decreased locomotor activity, reduced serum ferritin levels, albuminuria, thrombocytopenia (females only), and a reduced size of kidneys, adrenal glands, interscapular brown adipose tissue and liver, which is analogous to control mice on a low iron diet. Analysis of a second knockout model on the C57BL/6NCrl background reveals significant effects in metabolic cage experiments, including differences in body weight and lean body mass, day/night activity, food intake, and energy expenditure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
