| Primary Identifier | MGI:1270844 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 12684 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables lipid transfer activity; molecular adaptor activity; and phosphatidic acid binding activity. Involved in several processes, including COPII-coated vesicle cargo loading; lipid droplet fusion; and very-low-density lipoprotein particle assembly. Part of COPII vesicle coat. Is active in Golgi apparatus; endoplasmic reticulum membrane; and lipid droplet. Is expressed in autopod; dorsal root ganglion; and urinary system. Orthologous to human CIDEB (cell death inducing DFFA like effector b). PHENOTYPE: Mice homozygous for a knock-out allele display a lean phenotype, increased energy expenditure and improved insulin sensitivity and are resistant to high-fat diet-induced obesity, hyperlipidemia, or liver steatosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
