| Primary Identifier | MGI:1888526 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 57258 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable nuclear export signal receptor activity and small GTPase binding activity. Predicted to be involved in positive regulation of protein export from nucleus and protein export from nucleus. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system and retina. Orthologous to human XPO4 (exportin 4). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality before E10.5. Heterozygotes show male infertility, increased DNA damage in testes and the hippocampus, decrease in hippocampal neurons and impaired spatial memory. Mice homozygous for a gene trapped allele appear phenotypically normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
