Primary Identifier | MGI:2442811 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 268752 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Involved in positive regulation of fat cell differentiation. Located in cytoplasm. Is expressed in central nervous system; male reproductive system; and urinary system. Orthologous to human WDFY2 (WD repeat and FYVE domain containing 2). PHENOTYPE: Male mice homozygous for a null allele exhibit impaired glucose tolerance, insulin resistance, hepatic steatosis, increased gluconeogenesis and suppressed glycogen accumulation. [provided by MGI curators] |