Primary Identifier | MGI:2686058 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 382913 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule binding activity. Predicted to be involved in base-excision repair. Located in cytoplasm and mitotic spindle. Is expressed in primordial germ cell of gonad. Orthologous to human NEIL2 (nei like DNA glycosylase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased age-related DNA damage, loss of telomeres and increased induced lung inflammation. [provided by MGI curators] |