Primary Identifier | MGI:106916 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 110265 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables peptide-methionine (S)-S-oxide reductase activity. Predicted to be involved in cellular response to oxidative stress. Located in mitochondrion. Is expressed in several structures, including musculoskeletal system; nervous system; respiratory system; sensory organ; and testis. Orthologous to human MSRA (methionine sulfoxide reductase A). PHENOTYPE: Mice homozygous for disruptions in this allele display an increased sensitivity to oxidative stress, reductions in related enzyme levels, and reduced life spans. [provided by MGI curators] |