Primary Identifier | MGI:1918395 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 71145 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ferritin receptor activity. Involved in several processes, including intracellular iron ion homeostasis; iron ion transmembrane transport; and protein homotrimerization. Acts upstream of or within cellular response to heat. Located in cell surface and plasma membrane. Is expressed in several structures, including eye; gonad; heart; spinal cord; and vertebral pre-cartilage condensation. Orthologous to human SCARA5 (scavenger receptor class A member 5). PHENOTYPE: Homozygous deletion of this gene results in decreased male fertility and lymphocytic infiltration of the stroma of various tissues, particularly in the lungs. [provided by MGI curators] |