Primary Identifier | MGI:3045308 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 239167 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within labyrinthine layer blood vessel development; myoblast fusion involved in skeletal muscle regeneration; and skeletal muscle tissue development. Predicted to be located in plasma membrane. Is expressed in bone; extraembryonic component; placenta; and upper leg. Orthologous to human ERVFRD-1 (endogenous retrovirus group FRD member 1, envelope). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired syncytiotrophoblast layer II formation, growth retardation and partial preweaning lethality. [provided by MGI curators] |