| Primary Identifier | MGI:96223 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 15460 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription corepressor activity. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nuclear body. Is expressed in several structures, including alimentary system; brain; hair follicle; lower urinary tract; and sensory organ. Used to study alopecia universalis; atrichia with papular lesions; and hypotrichosis 4. Human ortholog(s) of this gene implicated in alopecia; alopecia universalis; and atrichia with papular lesions. Orthologous to human HR (HR lysine demethylase and nuclear receptor corepressor). PHENOTYPE: Mutant homozygotes exhibit hair loss, usually wrinkled skin with epidermal cysts. Females do not nurse their pups well. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
