Primary Identifier | MGI:3036290 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 239170 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Orthologous to human FHIP2B (FHF complex subunit HOOK interacting protein 2B). PHENOTYPE: Homozygous mice expressing a protein lacking exon 3 show increased susceptibility to induced colitis and colitis-associated colorectal cancer. Mice show an increase in bacailli and decrease in A. muciniphila in the microflora and exacerbated high-fat diet-induced steatohepatitis. [provided by MGI curators] |