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Protein Coding Gene : Fndc3a fibronectin type III domain containing 3A
Primary Identifier  MGI:1196463 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  319448
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Acts upstream of or within several processes, including Sertoli cell development; fertilization; and spermatid development. Located in acrosomal vesicle; cytosol; and vesicle membrane. Is expressed in brain; inner ear; limb; and submandibular gland primordium. Orthologous to human FNDC3A (fibronectin type III domain containing 3A).
PHENOTYPE: Males homozygous for an insertional mutation are sterile; females are fertile. In mutant males, spermatids form multinucleated syncytia and fail to mature, while Sertoli cells exhibit abnormal cytoplasmic vacuoles. [provided by MGI curators]
  • synonyms:
  • fibronectin type III domain containing 3A,
  • 1700094E19Rik,
  • MGI:2442045,
  • RIKEN cDNA F730017H24 gene,
  • MGI:98468,
  • D14Ertd453e,
  • sys,
  • MGI:1923886,
  • symplastic spermatids,
  • Fndc3,
  • DNA segment, Chr 14, ERATO Doi 453, expressed,
  • MGD-MRK-14691,
  • F730017H24Rik,
  • Fndc3a,
  • RIKEN cDNA 1700094E19 gene
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