| Primary Identifier | MGI:1341171 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 16840 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including endothelial cell morphogenesis; negative regulation of endothelial cell proliferation; and negative regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be located in extracellular region. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart valve; sensory organ; and skeleton. Orthologous to human CNMD (chondromodulin). PHENOTYPE: Homozygous mutant mice are viable and show no gross morphologic defects. While cartilage development and embryonic endochondral bone formation were found to be normal in mutant mice, one line of targeted mutants showed increased bone density and impairedbone resorption. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
