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Protein Coding Gene : Cldn10 claudin 10
Primary Identifier  MGI:1913101 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  58187
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables paracellular tight junction channel activity. Involved in paracellular transport. Located in bicellular tight junction; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including alimentary system; lung; metanephros; olfactory epithelium; and submandibular gland primordium. Orthologous to human CLDN10 (claudin 10).
PHENOTYPE: Mice lacking expression of this gene in the thick ascending limb of renal tubules display nephrocalcinosis, hypermagnesemia, and abnormalities in renal reabsorbtion. [provided by MGI curators]
  • synonyms:
  • Cldn10b,
  • DNA segment, Chr 14, ERATO Doi 728, expressed,
  • MGI:1289167,
  • 6720456I16Rik,
  • claudin 10B,
  • MGI:1925138,
  • Cldn10,
  • MGI:3696570,
  • RIKEN cDNA 6720456I16 gene,
  • claudin 10A,
  • Cldn10a,
  • D14Ertd728e,
  • claudin 10
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

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2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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