| Primary Identifier | MGI:88233 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 12274 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Involved in positive regulation of activation of membrane attack complex and positive regulation of angiogenesis. Acts upstream of or within in utero embryonic development. Predicted to be part of membrane attack complex. Predicted to be active in extracellular space. Is expressed in embryo. Human ortholog(s) of this gene implicated in complement component 6 deficiency. Orthologous to human C6 (complement C6). PHENOTYPE: Mice homozygous for a spontaneous mutation exhibit decreased susceptibility to ischemia reperfusion-induced renal injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
