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Protein Coding Gene : Fyb1 FYN binding protein 1
Primary Identifier  MGI:1346327 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  23880
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable lipid binding activity. Acts upstream of or within protein localization to plasma membrane. Located in plasma membrane. Part of protein-containing complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human FYB1 (FYN binding protein 1).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased T cell proliferation, thymocytes and platelet counts and decreased TCR-stimulated leukocyte adhesion. [provided by MGI curators]
  • synonyms:
  • FYN binding protein 1,
  • ADAP,
  • B630013F22Rik,
  • Fyb,
  • MGI:2443545,
  • FYN binding protein,
  • RIKEN cDNA B630013F22 gene,
  • MGI:7525417,
  • Fyb1,
  • FYB-120/130
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6 Pathways

Trail: ProteinCodingGene

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